Systematic Review and Meta-Analysis of Pre-Clinical Studies

MC-RWE >Systematic review and meta-analysis of pre-clinical studies

Systematic Review and Meta-Analysis of Pre-Clinical Studies

Pre-clinical studies (animal models) are important scientific tools which allow us for better understanding the etiology and pathophysiological mechanism(s) of human diseases. The animal models also help in studying the safety profile of investigational new drug (IND) in addition to efficacy parameters as well the mechanistic action(s) of IND. The evidence-based approach for conducting the systematic review and meta-analysis of pre-clinical studies; provide robust evidence for better understanding the impact of human diseases and its consequences; help in framing confirmatory trial approach which can improve data intensity for therapeutic target validation in clinical setting; at the same time light on the all possible mechanism of action(s) by which the IND acts in a specific medical condition.

Molecular Connections helps you in conducting systematic review and meta-analysis of pre-clinical studies through services including:

  • Strategic planning to design the study
  • Developing search strategy
  • Selecting studies for meta-analysis (evidence synthesis)
  • Systematic literature review
  • Manuscripts for peer review
  • Publication planning